Periodontal tissue engineering and regeneration: Consensus Report of the Sixth European Workshop on Periodontology.

AIM To review the scientific preclinical background and clinical studies of current methods of periodontal regeneration in the treatment of infrabony defects and soft tissue deficiencies. METHOD Five commissioned review papers including two systematic reviews were scrutinized by a group of experts in order to derive consensus conclusions, clinical relevance/implications and to propose future research requirements. RESULTS The following five papers were assessed: 1. Biological mediators and periodontal regeneration: a review of enamel matrix proteins at the cellular and molecular levels. 2. Regeneration of periodontal tissues: combination of barrier membranes and grafting materials - Biological foundation and preclinical evidence. 3. Clinical outcomes with bioactive agents alone or in combination with grafting or GTR 4. Treatment of gingival recession with coronally advanced flap procedures. A systematic review. 5. Soft tissue management at implant sites.